Drug Discovery & Development
Drug metabolism assays
In vitro metabolism assays are a part of the ADME (Absorption, Distribution, Metabolism, Elimination) tests and are used to evaluate the fate of pharmaceutical compounds, usually drugs, in the liver (hepatocytes) and extrahepatic tissues, such as intestines, kidneys, etc. The tests will identify metabolites and their structure, identify activated enzyme pathways, and measure in vitro degradation by screening.
• Molecules to be tested in sufficient quantity
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