Drug Discovery & Development
Hemolytic effect evaluation
Hemolysis potentially caused by molecules is often studied to demonstrate the safety/non-toxicity of these molecules in humans or animals. The release of intracellular hemoglobin (red chromoprotein) is used to evaluate hemolysis.
Red blood cells (human or animal) are incubated with the test compound or with a control detergent. The hemoglobin release is then measured and compared to the control lysis.
• Compound to test
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