Humanization by CDR-Grafting
The humanization of antibodies reduces the potential immunogenicity of a mouse parental antibody in a human context and increases its stability. These experiments include the integration of variable regions (CDRs) of a "parental" monoclonal antibody into a human immunoglobulin structure and optimizing this integration and then expressing the antibodies.
In this service, it is possible to select different options such as the sequence optimization or chimeric antibody expression.
• Hybridomas expressing the antibodies to humanize
• Informations regarding the hybridomas
Further details on the project may be requested directly by the expert. You will be able to exchange directly with the experts after filling in the form below.
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