Sequence and modifications analysis by LC-MS/MS
LC-MS/MS is a technique that is constituted by two components: a liquid chromatography system and a tandem mass spectrometer. LC-MS/MS is very sensitive and particularly well suited for the identification of proteins in a complex mixture. It also allows for the detection of post-translational modifications such as phosphorylation or ubiquitination.
• Samples to analyze in sufficient amount
• Description of your samples
• Description of the treatments done to the samples (including buffer composition)
• Size of the proteins of interest
• Picture of the gel
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