Identification of antibody cross-reactivity

Drug Discovery & Development In silico Identification of antibody cross-reactivity

Service description

Based on a technique that analyses the similarity of sequences and the structure of CDR (Complementarity Determining Region) of known antibodies and a new antibody. It allows identify possible cross-reactions of an antibody with other proteins ("off target"). These reactions may be positive or negative, but their knowledge is essential before the start of a clinical trial.

Materials to provide

• Antibody sequence
Further details on the project may be requested directly by the expert. You will be able to exchange directly with the experts after filling in the form below.

Delivrable(s)

  • PDB files of the 30 top-ranked antibody-antigen complexes structures
  • Peptides sequences
  • Raw and analyzed experimental data
  • Complete report with validation methods
  • Study following the specifications validated with the Expert

Your project

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