In vivo - target validation & efficacy

Drug Discovery & Development In vivo models In vivo - target validation & efficacy

Service description

Target identification and validation characterizes the role of a protein or pathway of interest and provides selection arguments to define the required properties of the compounds to be screened. The main strategies involved in target validation are gene knock-out studies, knock-down by antisense RNA or RNA interference, and direct inhibition of proteins by small molecules, peptides, antibodies, aptamers, or any other class of inhibitors.

Materials to provide

• Model
• Compounds to be tested
Further details on the project may be requested directly by the expert. You will be able to exchange directly with the experts after filling in the form below.

Delivrable(s)

  • Assesment of specific process
  • General toxicity assessment of drug screening
  • Study following the specifications validated with the Expert

Your project

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