PDX - Efficacy study

Drug Discovery & Development In vivo models PDX - Efficacy study

Service description

Patient-Derived Xenograft (PDX) models are tumor models based on cancerous tissue from patients (solid tumors) or cellular samples (hematological diseases) implanted in immunodeficient mice. These models reproduce more accurately than cell lines the biological characteristics of the cancers from which they are derived. In this experiment, you will be able to select experts to carry out preclinical tests (pilot test) to test anti-cancer molecules or other tests that you would like to perform on tumours.

Materials to provide

• Compounds or antibodies to test and controls
Further details on the project may be requested directly by the expert. You will be able to exchange directly with the experts after filling in the form below.

Delivrable(s)

  • Number of mice necessary for the study chosen
  • IV or IP dosing, oral dosing
  • Bi-weekly measurement of the tumor size and body weight
  • Necropsy and tumor collection and up to three tissues or blood
  • Cage observation
  • Analytical report of the study
  • Study following the specifications validated with the Expert

Your project

Please answer all questions below to specify your requirements