Generation of de novo specific ligands

Bioprocess Proteins Generation of de novo specific ligands

Service description

It is a technology that allows the de novo generation of artificial protein ligands to identify a target of interest. The use of protein ligands is a stable and simple alternative to the production of monoclonal antibodies that do not present a risk of post-translational modifications. The methodology combines ribosome display, next-generation sequencing, and bioinformatics technologies. The production of ligands in E. coli is reproducible, inexpensive and GMP-compatible.

Materials to provide

• Sample sequence if known
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Delivrable(s)

  • Determination of binder with high affinity against the target of interest
  • Identification of binder sequences
  • Study following the specifications validated with the Expert

Your project

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