Antiviral / virucidal effect analysis on norovirus model
The norovirus is responsible for human intestinal infection (gastroenteritis). This highly contagious virus is very resistant to virucidal solutions. The use of human norovirus is limited to L3 laboratories. For this reason, many laboratories use a norovirus model: MNV-1 (murine virus) and FCV (feline virus) that can be used in Laboratory L2.
The assay consists of determining the reduction of the infectious titer on RAW 264.7 and CRFK cells, or by using a plaques assay to measure the presence of living viruses.
• Compounds to test
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