Molecular combing analysis

Biostatistics 300

Service description

  • The molecular combing technique is used on the genome to stretch individual DNA molecules to prepare them for hybridization.
  • This allows direct visualization of DNA at the scale of the individual molecule.
  • The molecular combing system simultaneously stretches and collects millions of DNA molecules on the surface of a glass lamella, the process applies to DNA molecule sizes exceeding the megabase.
  • The technique is compatible with pre-labeled DNA and in situ hybridization.
  • No amplification is required; therefore, no bias is introduced into the analysis.

Materials to provide

  • Samples to analyze.

  • Further details on the project may be requested.
  • You will be able to exchange directly with the experts after filling in the form below.

Typical deliverables

  • Probes design.
  • Study following the specifications validated with the Expert.
Capture d’écran 2020-10-16 à 10.57.43

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