Antibody-antigen interaction measurement by SPR

Analytical methods Surface dynamics Antibody-antigen interaction measurement by SPR

Service description

Surface plasmon resonnance is a very powerful technique that allows for the characterization of interactions (ka, kd, KD) between two molecules. In this case, the expert will look at the kinetics of the interaction between an antibody and its potential antigen, using the strategy that is the most suited for the experimental conditions. For example, this is particularly useful when trying to identify which antibody has the most appropriate binding to the antigen of interest.

Materials to provide

• Antibodies and antigens in sufficient amount
• Description of antigen purification conditions
• Description of the buffers
Further details on the project may be requested directly by the expert. You will be able to exchange directly with the experts after filling in the form below.

Delivrable(s)

  • Optimization of the assay
  • Full data collection (ka & kd)
  • Analysis and interaction ranking
  • Data report
  • Study following the specifications validated with the Expert

Your project

Please answer all questions below to specify your requirements