Respiratory diseases refer to a group of illnesses that affect the respiratory system, including the lungs, bronchi, trachea, and alveoli. These diseases can range from mild, such as the common cold, to severe, such as pneumonia and tuberculosis.
Examples of respiratory diseases include asthma, bronchitis, COPD, cystic fibrosis, lung cancer, and COVID-19 (caused by the SARS-CoV-2 virus).
Mucus and other material coughed up from the lungs, can be analyzed for the presence of bacteria, viruses, or other pathogens.
This is a sample of fluid taken from the lungs through a bronchoscope and can be used to assess lung function and the presence of inflammation or infection.
Blood can be analyzed for biomarkers associated with respiratory disorders, such as inflammation, oxidative stress, or immune responses.
Samples taken from the nose or throat can be used to detect respiratory viruses or other pathogens.
In some cases, small tissue samples from the lung can be collected through a biopsy procedure and analyzed for evidence of disease or infection.
Please answer the fields below to be contacted by our team of scientists
There are several experimental models used in respiratory disorder research and development, including:
Cell culture models: utilizing human or animal cells in vitro to study cellular processes and interactions.
Animal models: using animals such as mice, rats, and rabbits to study the physiological and pathological effects of respiratory disorders.
Organoids models: three-dimensional structures grown from stem cells or other cell types to resemble organs and allow for the study of cellular interactions.
Ex vivo models: utilizing human tissues obtained from biopsy or surgical specimens to study the molecular and cellular mechanisms of respiratory disorders.
Patient-derived xenografts (PDXs): using human tumor tissue implanted into immunocompromised mice to study the effects of the disease in a living organism.
Microfluidic models: utilizing microfluidic chips to recreate the complex fluid dynamics of the respiratory system in a controlled environment.
In silico models: using computer simulations to study the physiological and pathological processes of respiratory disorders.
These models are used to study various aspects of respiratory disorders, including pathogenesis, drug efficacy, and disease progression.
Perform a feasibility study by looking for existing samples already in collections & ready to be transferred
Set up a clinical biological collection and preparing contracts with sources
Assist the material transfer from the source to the lab, including treatments, QA or shipping, as needed