Cytotoxicity - In vitro models
These tests are performed depending on the role of the therapeutic antibody to be designed. If the antibody must be able to activate an immune response by triggering NK cells and bispecific antibodies, cell-mediated cytotoxicity will be used. In the case of an antibody with a target expressed on the surface of the cancer cells, direct cytotoxicity testing could be performed.
Materials to provide
- Cells / compounds to be tested
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