Hemolysis potentially caused by molecules is often studied to demonstrate the safety/non-toxicity of these molecules in humans or animals. The release of intracellular hemoglobin (red chromoprotein) is used to evaluate hemolysis. Red blood cells (human or animal) are incubated with the test compound or with a control detergent. The hemoglobin release is then measured and compared to the control lysis.
Materials to provide
- Samples in sufficient amount
- Description of the samples
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- Assay as required
- Comparative analysis
- Study following the specifications validated with the Expert
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