The inflammation reaction is a protective reaction of the body against aggression/infection. However, inflammation in the absence of an aggressor (autoimmune inflammation) or uncontrolled over time (chronic inflammation) and/or in space (generalized inflammation) is harmful to the body. It is, therefore, necessary to look for anti-inflammatory molecules. Two types of tests are proposed: a cell test to report the activity of the NFkB promoter, and a test on non-reporting cells to measure inflammation markers.
Materials to provide
- Compounds to test
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- In vitro assays set up
- Effect results analysis
- Study following the specifications validated with the Expert
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