Fourier transform infrared spectroscopy (FTIR) is a highly sensitive technique to study structural changes.
In this service, it can be used to compare biosimilar candidates with the original molecule.
Several critical parameters can be analyzed:their three-dimensional structure, their glycosylation profile, the protein concentration, and the concentration of certain excipients such as Tween.
Materials to provide
Samples to analyze.
Description of the buffer.
Sample preparation protocol if applicable.
Further details on the project may be requested.
You will be able to exchange directly with the experts after filling in the form below.
Typical deliverables
Preparation of the samples.
FTIR analysis.
Prediction of secondary structure composition.
Protein concentration (based on the number of peptidic bonds).
Glycosylation comparison.
Excipient concentration.
Study report.
Study following the specifications validated with the Expert.
Get started with your biosimilars comparison study
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