Biosimilars comparison study

FTIR analysis

Service description

Fourier transform infrared spectroscopy (FTIR) is a highly sensitive technique to study structural changes. In this service, it can be used to compare biosimilar candidates with the original molecule. Several critical parameters can be analyzed: their three-dimensional structure, their glycosylation profile, the protein concentration and the concentration of certain excipients such as Tween.

Materials to provide

  • Samples to analyze
  • Description of buffer
  • Sample preparation protocol if applicable

    You will be able to exchange directly with the experts after filling in the form below.

    Further details on the project may be requested.

 

Typical deliverables

  • Preparation of the samples
  • FTIR analysis
  • Prediction of secondary structure composition
  • Protein concentration (based on number of peptidic bonds)
  • Glycosylation comparisation
  • Excipient concentration
  • Study report
  • Study following the specifications validated with the Expert

Get started with your biosimilars comparison study

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