In vivo target validation & efficacy

in vivo models 300

Service description

  • Target identification and validation characterize the role of a protein or pathway of interest and provide selection arguments to define the required properties of the compounds to be screened.
  • The main strategies involved in target validation are gene knock-out studies, knock-down by antisense RNA or RNA interference, and direct inhibition of proteins by small molecules, peptides, antibodies, aptamers, or any other class of inhibitors.

Materials to provide

  • Samples to test.
  • Model (if applicable).

  • Further details on the project may be requested.
  • You will be able to exchange directly with the experts after filling in the form below.

Typical deliverables

  • Assessment of specific processes.
  • General toxicity assessment of drug screening.
  • Study following the specifications validated with the Expert.
Capture d’écran 2020-10-16 à 10.57.43

Get started with your in vivo target validation project

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