In vivo target validation & efficacy
Target identification and validation characterize the role of a protein or pathway of interest and provide selection arguments to define the required properties of the compounds to be screened. The main strategies involved in target validation are gene knock-out studies, knock-down by antisense RNA or RNA interference, and direct inhibition of proteins by small molecules, peptides, antibodies, aptamers, or any other class of inhibitors.
Materials to provide
- Samples to test
- Model (if applicable)
Further details on the project may be requested.
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- Assesment of specific process
- General toxicity assessment of drug screening
- Study following the specifications validated with the Expert
Get started with your in vivo target validation project
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