In vivo target validation & efficacy

3a - Models

Service description

Target identification and validation characterize the role of a protein or pathway of interest and provide selection arguments to define the required properties of the compounds to be screened. The main strategies involved in target validation are gene knock-out studies, knock-down by antisense RNA or RNA interference, and direct inhibition of proteins by small molecules, peptides, antibodies, aptamers, or any other class of inhibitors.

Materials to provide

  • Samples to test
  • Model (if applicable)

    Further details on the project may be requested.

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Typical deliverables

  • Assesment of specific process
  • General toxicity assessment of drug screening
  • Study following the specifications validated with the Expert

Get started with your in vivo target validation project

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