PDX - in vivo efficacy study

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Service description

  • Patient-Derived Xenograft (PDX) models are tumor models based on cancerous tissue from patients (solid tumors) or cellular samples (hematological diseases) implanted in immunodeficient mice.
  • These models reproduce more accurately than cell lines the biological characteristics of the cancers from which they are derived.
  • In this experiment, you will be able to select experts to carry out preclinical tests (pilot test) to test anti-cancer molecules or other tests that you would like to perform on tumors.

Materials to provide

  • Compounds or antibodies to test and control.

  • Further details on the project may be requested.
  • You will be able to exchange directly with the experts after filling in the form below.

Typical deliverables

  • Number of mice necessary for the study chosen.
  • IV or IP dosing, oral dosing.
  • Bi-weekly measurement of the tumor size and body weight.
  • Necropsy and tumor collection and up to three tissues or blood.
  • Cage observation.
  • Analytical report of the study.
  • Study following the specifications validated with the Expert.
Capture d’écran 2020-10-16 à 10.57.43

Get started with your in vivo PDX efficacy project

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