Phosphoproteomics looks at the phosphorylation of proteins as a post-translational modification in a set of samples by mass spectrometry. Phosphorylation is a key modification that can be reversible, and that is involved in many cellular functions and pathways. Phosphoproteomics covers two main goals: understanding which protein or pathway is activated in a sample, and determining which proteins might be a potential candidate for a drug target.
Materials to provide
- Samples description
- Specificly required analysis
Further details on the project may be requested.
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- Treatment of the samples
- Protein extraction
- Digestion (i.e. trypsin digestion) of the samples
- Peptide preparation and LC MS/MS read
- Qualitative data analysis
- Report file
- Study following the specifications validated with the Expert
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