Assays on human intestinal and hepatic explants

Ex vivo 300

Service description

  • The use of in vitro tests on isolated human cells and in vivo tests on animal models has limitations: the failure to take into account the tissue complexity for isolated cells and the failure to guarantee the possibility of extrapolating data obtained from animals to humans.
  • For this reason, the use of human explants of the stomach, intestine, skin, or liver, provides a way to test the compounds on a complex human model closer to the physiological reality than isolated cells.
  • Several tests are available: viability, barrier function for intestinal explants, absorption and metabolism function, immune function, and infection by pathogenic bacteria for skin and intestinal explants.

Materials to provide

  • Products to be tested.
  • Conditions of testing.

  • Further details on the project may be requested.
  • You will be able to exchange directly with the experts after filling in the form below.

Typical deliverables

  • Explants.
  • Assay set up.
  • Study following the specifications validated with the Expert.
  • Experimentation as required.
  • Analysis and report.

Get started with your intestinal and hepatic explants testing project

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