In silico identification of antibody cross-reactivity
Service description
Based on a technique that analyses the similarity of sequences and the structure of CDR (Complementarity Determining Region) of known antibodies and a new antibody.
It allows the identification of possible cross-reactions of an antibody with other proteins ("off-target").
These reactions may be positive or negative, but their knowledge is essential before the start of a clinical trial.
Materials to provide
Antibody sequence.
Further details on the project may be requested.
You will be able to exchange directly with the experts after filling in the form below.
Typical deliverables
PDB files of the 30 top-ranked antibody-antigen complexes structures.
Peptides sequences.
Raw and analyzed experimental data.
Complete the report with validation methods.
Study following the specifications validated with the Expert.
Get started with your in silico identification of antibody cross-reactivity project
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