Heart and Vascular Diseases
What is the role of biobanks?
Biobanks (also known as biological resource centers) are entities responsible for the management of biological samples and their associated data. These structures can collect and preserve heart and vascular disease sample from sick patients in the form of samples inventory.
Cardiovascular diseases are the leading cause of death worldwide and the second in France. They include all diseases affecting the heart and blood vessels, the main ones being myocardial infarction (MI), stroke, cardiomyopathy, heart failure and heart arrhythmia.
More generally, these diseases fall into two categories. Those affecting the heart such as congenital heart defects, and those affecting the blood vessels and the organs they feed : coronary heart disease (CHD), cerebrovascular disease, peripheral artery disease (PAD), venous thrombosis and pulmonary embolisms (PE).
Biobanks collect and store biological samples from patients with cardiovascular disease. Some samples are made available for research: nucleic acid extractions, tissue blocks and organs, blood and its derivatives etc.
What are the advantages of using a biobank for cardiovascular disease sample needs?
Setting up a biological collection and preparing samples for a clinical project
Save time in the experimentation phase
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Setting up a collection of biological samples
After a biopsy, or other procedure to retrieve a human sample, a sample may be retained, with the patient's consent, for research purposes.
Storage of clinical samples
The samples, after collection, must be stored under certain conditions, depending on their type and shelf life, to allow for their viability.